Live Updates
  • PLASMA THERAPY FOR COVID-19 1 World 20,145,818
    World
    Confirmed: 20,145,818
    Active: 6,419,035
    Recovered: 12,990,691
    Death: 736,092
  • PLASMA THERAPY FOR COVID-19 2 USA 5,218,584
    USA
    Confirmed: 5,218,584
    Active: 2,378,909
    Recovered: 2,673,846
    Death: 165,829
  • PLASMA THERAPY FOR COVID-19 3 Brazil 3,039,349
    Brazil
    Confirmed: 3,039,349
    Active: 819,620
    Recovered: 2,118,460
    Death: 101,269
  • PLASMA THERAPY FOR COVID-19 4 India 2,266,954
    India
    Confirmed: 2,266,954
    Active: 641,333
    Recovered: 1,580,269
    Death: 45,352
  • PLASMA THERAPY FOR COVID-19 5 Russia 892,654
    Russia
    Confirmed: 892,654
    Active: 180,972
    Recovered: 696,681
    Death: 15,001
  • PLASMA THERAPY FOR COVID-19 6 South Africa 559,859
    South Africa
    Confirmed: 559,859
    Active: 137,977
    Recovered: 411,474
    Death: 10,408
  • PLASMA THERAPY FOR COVID-19 7 Peru 478,024
    Peru
    Confirmed: 478,024
    Active: 132,932
    Recovered: 324,020
    Death: 21,072
  • PLASMA THERAPY FOR COVID-19 8 Chile 375,044
    Chile
    Confirmed: 375,044
    Active: 17,563
    Recovered: 347,342
    Death: 10,139
  • PLASMA THERAPY FOR COVID-19 9 Spain 361,442
    Spain
    Confirmed: 361,442
    Active: 332,939
    Recovered: ?
    Death: 28,503
  • PLASMA THERAPY FOR COVID-19 10 Iran 328,844
    Iran
    Confirmed: 328,844
    Active: 23,586
    Recovered: 286,642
    Death: 18,616
  • PLASMA THERAPY FOR COVID-19 11 UK 311,641
    UK
    Confirmed: 311,641
    Active: 265,115
    Recovered: ?
    Death: 46,526
  • PLASMA THERAPY FOR COVID-19 12 Pakistan 284,660
    Pakistan
    Confirmed: 284,660
    Active: 17,799
    Recovered: 260,764
    Death: 6,097
  • PLASMA THERAPY FOR COVID-19 13 Bangladesh 260,507
    Bangladesh
    Confirmed: 260,507
    Active: 106,632
    Recovered: 150,437
    Death: 3,438
  • PLASMA THERAPY FOR COVID-19 14 Turkey 241,997
    Turkey
    Confirmed: 241,997
    Active: 11,169
    Recovered: 224,970
    Death: 5,858
  • PLASMA THERAPY FOR COVID-19 15 Germany 217,563
    Germany
    Confirmed: 217,563
    Active: 10,403
    Recovered: 197,900
    Death: 9,260
  • PLASMA THERAPY FOR COVID-19 16 France 197,921
    France
    Confirmed: 197,921
    Active: 84,761
    Recovered: 82,836
    Death: 30,324
  • PLASMA THERAPY FOR COVID-19 17 Qatar 113,262
    Qatar
    Confirmed: 113,262
    Active: 3,081
    Recovered: 109,993
    Death: 188
  • PLASMA THERAPY FOR COVID-19 18 China 84,668
    China
    Confirmed: 84,668
    Active: 802
    Recovered: 79,232
    Death: 4,634
  • PLASMA THERAPY FOR COVID-19 19 Ukraine 81,957
    Ukraine
    Confirmed: 81,957
    Active: 35,676
    Recovered: 44,359
    Death: 1,922
  • PLASMA THERAPY FOR COVID-19 20 Belgium 74,152
    Belgium
    Confirmed: 74,152
    Active: 46,500
    Recovered: 17,780
    Death: 9,872
  • PLASMA THERAPY FOR COVID-19 21 Singapore 55,292
    Singapore
    Confirmed: 55,292
    Active: 5,656
    Recovered: 49,609
    Death: 27
  • PLASMA THERAPY FOR COVID-19 22 Poland 52,410
    Poland
    Confirmed: 52,410
    Active: 13,724
    Recovered: 36,877
    Death: 1,809
  • PLASMA THERAPY FOR COVID-19 23 Switzerland 36,708
    Switzerland
    Confirmed: 36,708
    Active: 2,421
    Recovered: 32,300
    Death: 1,987
  • PLASMA THERAPY FOR COVID-19 24 Austria 22,106
    Austria
    Confirmed: 22,106
    Active: 1,373
    Recovered: 20,010
    Death: 723
  • PLASMA THERAPY FOR COVID-19 25 Australia 21,407
    Australia
    Confirmed: 21,407
    Active: 9,217
    Recovered: 11,876
    Death: 314
  • PLASMA THERAPY FOR COVID-19 26 Thailand 3,351
    Thailand
    Confirmed: 3,351
    Active: 133
    Recovered: 3,160
    Death: 58

PLASMA THERAPY FOR COVID-19

Plasma is the often forgotten part of blood. White blood cells, red blood cells, and platelets are important to body function. But plasma also plays a key role. This fluid carries the blood components throughout the body.

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India COVID updates

Active  cases:- 20835

Cured:- 6184

Death:- 872

States with max number of cases in India till now:-

1) Maharashtra:- 7628

2) Gujrat:- 3071

3) Delhi:- 2625

4) MP:- 2096

5) Rajasthan:-  2083

What is plasma and what are platelets?

Plasma is the liquid portion of whole blood. It is composed largely of water and proteins, and it provides a medium for red blood cells, white blood cells, and platelets to circulate through the body. Platelets, also called thrombocytes, are blood cells that cause blood clots and other necessary growth healing functions.

Platelet activation plays a key role in the body’s natural healing process.

What is Antibody?

Glycoprotein molecules produced by plasma cells also known immunoglobulin, it is Y shaped protein part of the immune system (IS). The antibody recognizes a unique molecule of the pathogen (virus, bacteria). The antibody attaches to the unique molecule and activates another part of IS to attack the foreign antigen (Ag). Antibodies are secreted by B-cells of the immune system. Production of Ab is the main function of humoral immunity. Consist of 4 polypeptides 2 heavy and light chains, in variable & constant region. Its structure also contain fab (fragment antigen binding)  & FC (fragment crystallizable) region.

PLASMA THERAPY FOR COVID-19 28

 What is Plasma?

Plasma is part of blood. When we centrifuge blood clearly 3 layers are observed. 1st layer contains a yellowish alkaline fluid called plasma. Followed by WBC & platelets & then RBC. Plasma makes up about 55% of the total blood volume. Plasma contain 90-92% water & 8-10% suspended & dissolved substances. Plasma proteins (serum albumin. Globulin, herein, prothrombin, fibrinogen) & nitrogenous wastes (urea & uric acid ) are present in the blood.

PLASMA THERAPY FOR COVID-19 29

What is convalescent?

A person recovered or recovering from illness or any medical treatment is called convalescent.

About Convalescent plasma therapy (CPT)

When people get sick with bacteria or virus their body produce Antibodies to fight specifically that antigen which causes illness.

When the attack by pathogen our body produces Ab. If the body produces sufficient Ab we can recover from the illness easily. This recovered immunity can be transfer to a sick person. As we know there is no COVID vaccine yet, so this therapy can be the best source.

This method has also been used in the past in 1918 for a flu epidemic, the outbreak of Ebola as well as other coronaviruses like SARS, MERS (middle east respiratory syndrome), H1N1, H5N1, etc.

The study conducted:-

A study published  JAMA on 27 march 2020 conducted in Shenzhen china’s conclusion was this preliminary uncontrolled case series of  5 critically ill patients with Covid-19 & ARDS administration of CP containing neutralizing Ab shown improvement in their clinical status.

USA 6 April 2020 10 severe patients were enrolled. They were given 200ml of one dose of CP which was derived from recently recovered donors. They neutralize Ab titers above 1:640. The clinical symptoms were significantly improved along with increasing oxyhemoglobin saturation within 3 days. They found that the viral load was undetectable after transfusion in seven patients. No adverse effect was observed. The study shows CP therapy was well tolerated & could potentially improve the clinical outcomes.

Who can be the plasma donor?

  1. The person with complete resolution of symptoms at least 14 days prior to the donation of plasma.
  2. Prior diagnosis of Covid-19.
  3. Negative PCR result for Covid-19.

Is this the cure for COVID 19?

No, it is not a cure, it is just a stop-gap measure until better treatment or vaccine is available. Only it will be used for those people who are not in critical condition.

News update:-

India 1st COVID-19 patient treated with CPT recovers. The 40-year-old man from Delhi was tested positive on 4th April for COVID-19.  He developed pneumonia with type 1 respiratory failure. He was put into ventilator support on 8th April. His family came forward to arrange a donor for plasma extraction. As per the criteria of the donor is again went for the test for COVID-19  result was negative. The donor fits under all the standard rule out Hepatitis B, Hepatitis C  & HIV. He was treated on the night of 14th April. After receiving treatment he sowed progressive improvement & 4th day was off the ventilator. I started taking oral feed within 24 hours of being off the ventilator.

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