Plasma Therapy For Covid 19

Live Updates
  • Best Plasma Therapy For Covid 19 1 World 596,496,496
    World
    Confirmed: 596,496,496
    Active: 19,254,394
    Recovered: 570,783,673
    Death: 6,458,429
  • Best Plasma Therapy For Covid 19 2 USA 94,869,936
    USA
    Confirmed: 94,869,936
    Active: 3,648,779
    Recovered: 90,158,070
    Death: 1,063,087
  • Best Plasma Therapy For Covid 19 3 India 44,284,135
    India
    Confirmed: 44,284,135
    Active: 118,193
    Recovered: 43,638,844
    Death: 527,098
  • Best Plasma Therapy For Covid 19 4 France 34,240,336
    France
    Confirmed: 34,240,336
    Active: 550,566
    Recovered: 33,536,528
    Death: 153,242
  • Best Plasma Therapy For Covid 19 5 Brazil 34,201,280
    Brazil
    Confirmed: 34,201,280
    Active: 431,655
    Recovered: 33,087,797
    Death: 681,828
  • Best Plasma Therapy For Covid 19 6 Germany 31,599,085
    Germany
    Confirmed: 31,599,085
    Active: 1,117,847
    Recovered: 30,335,400
    Death: 145,838
  • Best Plasma Therapy For Covid 19 7 UK 23,420,826
    UK
    Confirmed: 23,420,826
    Active: 194,448
    Recovered: 23,040,291
    Death: 186,087
  • Best Plasma Therapy For Covid 19 8 Russia 18,931,140
    Russia
    Confirmed: 18,931,140
    Active: 375,833
    Recovered: 18,172,070
    Death: 383,237
  • Best Plasma Therapy For Covid 19 9 Turkey 16,528,070
    Turkey
    Confirmed: 16,528,070
    Active: 105,759
    Recovered: 16,322,253
    Death: 100,058
  • Best Plasma Therapy For Covid 19 10 Spain 13,306,301
    Spain
    Confirmed: 13,306,301
    Active: 215,825
    Recovered: 12,978,570
    Death: 111,906
  • Best Plasma Therapy For Covid 19 11 Australia 9,830,302
    Australia
    Confirmed: 9,830,302
    Active: 214,863
    Recovered: 9,602,480
    Death: 12,959
  • Best Plasma Therapy For Covid 19 12 Iran 7,488,493
    Iran
    Confirmed: 7,488,493
    Active: 155,070
    Recovered: 7,190,330
    Death: 143,093
  • Best Plasma Therapy For Covid 19 13 Poland 6,120,834
    Poland
    Confirmed: 6,120,834
    Active: 668,155
    Recovered: 5,335,906
    Death: 116,773
  • Best Plasma Therapy For Covid 19 14 Ukraine 5,030,389
    Ukraine
    Confirmed: 5,030,389
    Active: 7,577
    Recovered: 4,914,069
    Death: 108,743
  • Best Plasma Therapy For Covid 19 15 Austria 4,832,311
    Austria
    Confirmed: 4,832,311
    Active: 73,540
    Recovered: 4,739,492
    Death: 19,279
  • Best Plasma Therapy For Covid 19 16 Thailand 4,623,596
    Thailand
    Confirmed: 4,623,596
    Active: 19,709
    Recovered: 4,571,997
    Death: 31,890
  • Best Plasma Therapy For Covid 19 17 Belgium 4,453,483
    Belgium
    Confirmed: 4,453,483
    Active: 94,653
    Recovered: 4,326,466
    Death: 32,364
  • Best Plasma Therapy For Covid 19 18 Chile 4,393,244
    Chile
    Confirmed: 4,393,244
    Active: 41,629
    Recovered: 4,291,587
    Death: 60,028
  • Best Plasma Therapy For Covid 19 19 Peru 4,031,007
    Peru
    Confirmed: 4,031,007
    Active: 98,097
    Recovered: 3,717,882
    Death: 215,028
  • Best Plasma Therapy For Covid 19 20 South Africa 4,008,443
    South Africa
    Confirmed: 4,008,443
    Active: 8,854
    Recovered: 3,897,607
    Death: 101,982
  • Best Plasma Therapy For Covid 19 21 Switzerland 3,993,681
    Switzerland
    Confirmed: 3,993,681
    Active: 109,456
    Recovered: 3,870,104
    Death: 14,121
  • Best Plasma Therapy For Covid 19 22 Bangladesh 2,009,222
    Bangladesh
    Confirmed: 2,009,222
    Active: 27,943
    Recovered: 1,951,965
    Death: 29,314
  • Best Plasma Therapy For Covid 19 23 Singapore 1,801,936
    Singapore
    Confirmed: 1,801,936
    Active: 82,468
    Recovered: 1,717,903
    Death: 1,565
  • Best Plasma Therapy For Covid 19 24 Pakistan 1,563,705
    Pakistan
    Confirmed: 1,563,705
    Active: 11,365
    Recovered: 1,521,803
    Death: 30,537
  • Best Plasma Therapy For Covid 19 25 Qatar 420,895
    Qatar
    Confirmed: 420,895
    Active: 5,565
    Recovered: 414,649
    Death: 681
  • Best Plasma Therapy For Covid 19 26 China 236,261
    China
    Confirmed: 236,261
    Active: 6,347
    Recovered: 224,688
    Death: 5,226

Plasma Therapy For Covid 19 Plasma is the often forgotten part of blood. White blood cells, red blood cells, and platelets are important to body function. But plasma also plays a key role. This fluid carries the blood components throughout the body.

Plasma Therapy For Covid 19
Plasma Therapy For Covid 19

What Is Plasma Therapy For Covid 19

Plasma is the liquid portion of whole blood. It is composed largely of water and proteins, and it provides a medium for red blood cells, white blood cells, and platelets to circulate through the body. Platelets, also called thrombocytes, are blood cells that cause blood clots and other necessary growth healing functions.

Platelet activation plays a key role in the body’s natural healing process.

What is Antibody?

Glycoprotein molecules produced by plasma cells also known immunoglobulin, it is Y shaped protein part of the immune system (IS). The antibody recognizes a unique molecule of the pathogen (virus, bacteria).

The antibody attaches to the unique molecule and activates another part of IS to attack the foreign antigen (Ag). Antibodies are secreted by B-cells of the immune system. Production of Ab is the main function of humoral immunity. Consist of 4 polypeptides 2 heavy and light chains, in variable & constant region. Its structure also contain fab (fragment antigen binding)  & FC (fragment crystallizable) region.

Best Plasma Therapy For Covid 19 27

 What is Plasma?

Plasma is part of blood. When we centrifuge blood clearly 3 layers are observed. 1st layer contains a yellowish alkaline fluid called plasma. Followed by WBC & platelets & then RBC. Plasma makes up about 55% of the total blood volume.

Plasma contain 90-92% water & 8-10% suspended & dissolved substances. Plasma proteins (serum albumin. Globulin, herein, prothrombin, fibrinogen) & nitrogenous wastes (urea & uric acid ) are present in the blood.

Best Plasma Therapy For Covid 19 28

What is convalescent?

A person recovered or recovering from illness or any medical treatment is called convalescent.

About Convalescent plasma therapy (CPT)

When people get sick with bacteria or virus their body produce Antibodies to fight specifically that antigen which causes illness.

When the attack by pathogen our body produces Ab. If the body produces sufficient Ab we can recover from the illness easily. This recovered immunity can be transfer to a sick person. As we know there is no COVID vaccine yet, so this therapy can be the best source.

This method has also been used in the past in 1918 for a flu epidemic, the outbreak of Ebola as well as other coronaviruses like SARS, MERS (middle east respiratory syndrome), H1N1, H5N1, etc.

The study conducted

A study published  JAMA on 27 march 2020 conducted in Shenzhen china’s conclusion was this preliminary uncontrolled case series of  5 critically ill patients with Covid-19 & ARDS administration of CP containing neutralizing Ab shown improvement in their clinical status.

USA 6 April 2020 10 severe patients were enrolled. They were given 200ml of one dose of CP which was derived from recently recovered donors. They neutralize Ab titers above 1:640. The clinical symptoms were significantly improved along with increasing oxyhemoglobin saturation within 3 days. They found that the viral load was undetectable after transfusion in seven patients. No adverse effect was observed. The study shows CP therapy was well tolerated & could potentially improve the clinical outcomes.

Who can be the plasma donor?

  1. The person with complete resolution of symptoms at least 14 days prior to the donation of plasma.
  2. Prior diagnosis of Covid-19.
  3. Negative PCR result for Covid-19.

Is this the cure for COVID 19?

No, it is not a cure, it is just a stop-gap measure until better treatment or vaccine is available. Only it will be used for those people who are not in critical condition.

Read More Articles…

News update:-

India 1st COVID-19 patient treated with CPT recovers. The 40-year-old man from Delhi was tested positive on 4th April for COVID-19.  He developed pneumonia with type 1 respiratory failure.

He was put into ventilator support on 8th April. His family came forward to arrange a donor for plasma extraction. As per the criteria of the donor is again went for the test for COVID-19  result was negative.

The donor fits under all the standard rule out Hepatitis B, Hepatitis C  & HIV. He was treated on the night of 14th April. After receiving treatment he sowed progressive improvement & 4th day was off the ventilator. I started taking oral feed within 24 hours of being off the ventilator.

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