Lehninger Principles Of Biochemistry Fourth Editions

Lehninger

PRINCIPLES OF
BIOCHEMISTRY
Fourth Edition

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Lehninger Principles Of Biochemistry Fourth Editions

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New to This Edition

Every chapter fully updated: Including coverage of the human genome and genomics
integrated throughout, and key developments since the publication of the third edition, such as
the structure of the ribosome.

New treatment of metabolic regulation: NEW Chapter 15 gives students the most up to–
date picture of how cells maintain biochemical homeostasis by including modern concepts in
metabolic regulation.

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Lehninger Principles of Biochemistry
Fourth Edition
David L. Nelson (U. of Wisconsin–Madison)
Michael M. Cox (U. of Wisconsin–Madison)
1. The Foundations of Biochemistry
1.1 Cellular Foundations
1.2 Chemical Foundations
1.3 Physical Foundations
1.4 Genetic Foundations
1.5 Evolutionary Foundations
Distilled and reorganized from Chapters 1–3 of the previous edition, this overview
provides a refresher on the cellular, chemical, physical, genetic, and evolutionary
background to biochemistry, while orienting students toward what is unique about
biochemistry.]

PART I. STRUCTURE AND CATALYSIS
2. Water
2.1 Weak Interactions in Aqueous Systems
2.2 Ionization of Water, Weak Acids, and Weak Bases
2.3 Buffering against pH Changes in Biological Systems
2.4 Water as a Reactant
2.5 The Fitness of the Aqueous Environment for Living Organisms
Includes new coverage of the concept of protein-bound water, illustrated with
molecular graphics.
3. Amino Acids, Peptides, and Proteins
3.1 Amino Acids
3.2 Peptides and Proteins
3.3 Working with Proteins
3.4 The Covalent Structure of Proteins
3.5 Protein Sequences and Evolution
Adds important new material on genomics and proteomics and their implications for
the study of protein structure, function, and evolution.
4. The Three-Dimensional Structure of Proteins
4.1 Overview of Protein Structure
4.2 Protein Secondary Structure
4.3 Protein Tertiary and Quaternary Structures
4.4 Protein Denaturation and Folding
Adds a new box on scurvy.

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5. Protein Function
5.1 Reversible Binding of a Protein to a Ligand: Oxygen-Binding Proteins
5.2 Complementary Interactions between Proteins and Ligands: The Immune
System and Immunoglobulins
5.3 Protein Interactions Modulated by Chemical Energy: Actin, Myosin, and
Molecular Motors
Adds a new box on carbon monoxide poisoning
6. Enzymes
6.1 An Introduction to Enzymes
6.2 How Enzymes Work
6.3 Enzyme Kinetics as An Approach to Understanding Mechanism
6.4 Examples of Enzymatic Reactions
6.5 Regulatory Enzymes

Molecular Biology Of The Cell

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